COLOTECT is a highly sensitive, non-invasive test for detecting colorectal cancer (CRC) and precancerous lesions. It analyzes fecal samples using specific PCR for multimethylation, identifying abnormal genetic markers associated with CRC. The detection of gene methylation status in exfoliated cells allows the identification of colorectal cancer and precancerous lesions, even in the absence of active bleeding.
Overview
Colorectal cancer is the third most common cancer.
The data presented here comes from the Global Cancer Observatory, owned by the World Health Organization/International Agency for Research on Cancer (last accessed 17 August 2022).
Colorectal cancer is the second most deadly cancer globally.
The data presented here comes from the Global Cancer Observatory, owned by the World Health Organization/International Agency for Research on Cancer (last accessed 17 August 2022).
The global survival rate for colorectal cancer varies, but in developed countries, the 5-year survival rate for early stages can reach 90%.
Moghimi-Dehkordi B, Safaee A. An overview of colorectal cancer survival rates and prognosis in Asia. World J Gastrointest Oncol. 2012;4(4):71-75. doi:10.4251/wjgo.v4.i4.71
When Should You Consider This Test?
Consider this test in the following cases:
Individuals aged 45 or older
Those with a family history of colorectal cancer
People with a personal history of polyps or cancer
Patients with inflammatory bowel diseases
Asymptomatic individuals who prefer a non-invasive test option
Individuals with difficulty or contraindication for undergoing colonoscopy
Genes Analyzed
The panel includes:
3
Genes
SDC2, ADHFE1 e PPP2R5C
Methodology
The methodology used for this test is as follows:
Sample:
Feces
PREPARATION:
Feces: No fasting required.
TURNAROUND TIME:
Up to 15 calendar days
REQUIRED DOCUMENTS:
Medical request.
Type
Description
Technique
Multiplex Fluorescent PCR
Sensitivity
87% Sensitive for CRC and 42.1% Sensitive for Colorectal Adenoma