MammaPrint is a genomic test used to assess the risk of breast cancer recurrence in women with early-stage breast cancer. It analyzes the activity of 70 specific genes in tumor tissue to determine the likelihood of cancer recurrence and, thus, helps guide decisions about the necessity of chemotherapy.
Overview
The combination of MammaPrint with other clinical and pathological factors is considered a robust approach for making treatment decisions in breast cancer.
LOW-RISK PATIENTS HAVE
1.3%
CHANCE OF RECURRENCE
The MINDACT trial determined that these patients do not benefit from chemotherapy.
HIGH-RISK PATIENTS HAVE
11.7%
CHANCE OF RECURRENCE
These patients showed significantly better outcomes with chemotherapy.
46%
Almost half of clinically high-risk patients were reclassified as MammaPrint low risk and could forgo chemotherapy without compromising their outcomes.
When Should You Consider This Test?
Consider this test in the following cases:
Patients with early-stage breast cancer
Stages I and II with tumors up to 5 cm in diameter
Patients with hormone receptor-positive (HR+)
and/or HER2-negative breast cancer.
Patients with node-negative breast cancer
or limited lymph node involvement (up to 3 affected nodes).